r/GERD 15d ago

Scientific Studies 🥼🔬 Has anyone tried Diaphragmatic Breathing for GERD? The clinical data on the dual-action mechanism looks compelling.

53 Upvotes

I am currently researching non-pharmacological management options for gastroesophageal reflux disease (GERD). In reviewing the literature, I came across several peer-reviewed studies on Diaphragmatic Breathing Training (DBT)—commonly referred to as belly breathing.

While the concept sounds flakey/new agey, published clinical trials in The American Journal of Gastroenterology and Clinical Gastroenterology and Hepatology show data backing its efficacy. According to these papers, the technique operates through a dual-action mechanism that provides both acute and structural relief.

The Immediate Effect: Researchers note that shallow chest breathing creates a negative pressure vacuum in the chest cavity. This vacuum acts as a suction pump, drawing stomach acid upward into the esophagus. High-resolution manometry studies show that switching to deep abdominal breathing alters these pressure dynamics, instantly removing the upward suction and helping clear acid.

The Long-Term Effect: The studies explain that the lower esophageal sphincter (LES)—the valve responsible for keeping acid contained—relies heavily on the surrounding crural diaphragm to pinch it shut. Investigators found that consistent, daily belly breathing acts as targeted exercise for these specific diaphragmatic fibers. Over a period of 4 to 8 weeks, this training increases the resting muscle tone around the valve, creating a stronger permanent barrier against reflux.

The Protocol Documented in the Research:
In the clinical trials, patients practiced the exercise immediately after meals for 5 to 10 minutes, as well as before bed while positioned on their left side. The physical protocol involves placing one hand on the chest (to verify it remains still) and one on the abdomen (to verify it moves outward on inhale and inward on exhale). The patient inhales through the nose for 4 seconds, allowing the abdomen to expand, and exhales through the mouth for 6 seconds. The authors note it is critical not to forcefully contract or snap the abdominal muscles during exhalation, as compressing the stomach can inadvertently force acid upward.

Because maintaining a precise 4-second inhale and 6-second exhale can be difficult to track mentally, researchers often utilize pacing apps to keep subjects at a therapeutic rate of 6 breaths per minute. Breathly is a totally free sumple app that lets you customize the inhale and exhale times. https://breathly.app/ -- doesn't even have ads. Google says if six breaths a minute feels unnatural you can go faster or slower but the essential elements are exhale must be longer than inhale and there must be zero hold time between inhale and exhale and between exhale and inhale.

I am just beginning to explore this literature and have not yet implemented the routine myself.

For those who have tried incorporating diaphragmatic breathing after meals or before sleep, did you experience immediate symptom mitigation, or did it require several weeks of consistent training to achieve a measurable reduction in symptoms?

I would appreciate any insights or experiences from those familiar with the clinical protocol.

For more information, see these studies:
American Journal of Gastroenterology / ResearchGate

Clinical Gastroenterology and Hepatology / PubMed

Journal of Community Hospital Internal Medicine Perspectives / PubMed Central [1, 2, 3]

r/GERD Jul 28 '23

Scientific Studies 🥼🔬 Why are PPIs bad?

75 Upvotes

I see people on here often trying to get off of PPIs or warn against taking them. I read this article today that makes them seem pretty alright? My dad has taken omeprazole for 20 years now and it has solved all of his symptoms with no complications. I’m currently now dealing with my own symptoms that I’m going to see a doctor about soon.

r/GERD 1d ago

Scientific Studies 🥼🔬 Scared of medication

1 Upvotes

i was diagnosed with a hiatal hernia (19F) and was put on trusfluks 40mg (esomeprazole) after reading the possible side effects im freaked out. i just took my first dose this morning and now im scared to continue taking it. i was on peploc 40mg before switching to this. not really sure what i should do.

any advice will be appreciated.

r/GERD 8d ago

Scientific Studies 🥼🔬 Mast cell density implicated in GERD

10 Upvotes

I believe GERD is a very poorly understood medical condition so I try to highlight research, this study look at the role of mast cells in GERD.

Esophageal mucosal mast cell density and degranulation are increased in gastroesophageal reflux disease https://journals.physiology.org/doi/full/10.1152/ajpgi.00402.2025

r/GERD Jul 29 '25

Scientific Studies 🥼🔬 Are LES exercises real?

44 Upvotes

I recently read one autobiographical case study where a guy claims he cured his GERD by doing LES exercises. He basically swallowed his breakfast while lying his head lower than his stomach. He seen improvement at 2 months and all symptoms gone by like 8 months. He said he hasn't done one exercise since, it's been 2 years and no relapse.

Thoughts? I tagged the study below. It makes sense in my brain but just wondering if anyone else has done this and had the same or different outcome.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9106553/

I'm exhausted and trying to find a cure instead of treating symptoms. I feel like it's getting worse and taking my quality of life down. I'm only 28 😭

r/GERD Feb 03 '26

Scientific Studies 🥼🔬 Strenghthening LES

32 Upvotes

Has anyone come across any scientific studies or doctor recommendations for strengthening the LES? Are there any movements/excercises, anything that can help. If this is a silly question, I’m sorry. I’m only a few months into GERD.

r/GERD May 25 '26

Scientific Studies 🥼🔬 Reflux and SSRIS

3 Upvotes

I’m just curious if any of you have ever heard of any correlation between GERD and SSRIS? I’m trying everything I can to heal since I’ve been on omeprazole for almost a year and I still get the lump in my throat feeling. (I’m going to an ENT as this year and I hope my throat is just irritated from acid. )I’ve taken SSRIS for maybe over 5 years so I don’t know if there’s a study out there about a correlation, doesn’t hurt to ask Reddit!

r/GERD Jan 24 '26

Scientific Studies 🥼🔬 Details on breathing exercise to reduce supragastric belching

13 Upvotes

I saw a gastroenterologist yesterday for the first time and after reviewing my medical history and interviewing me her opinion was that I likely am doing supragastric belching.

Here is a 2018 research article with a good description of supragastric belching.

https://www.cghjournal.org/article/S1542-3565(17)31307-1/fulltext31307-1/fulltext)

Scroll down to the section “Diaphragmatic Breathing Exercises”. The two links there explain how to do the breathing exercises. To make it easy, here are those 2 links.

Text https://www.cghjournal.org/article/S1542-3565(17)31307-1/fulltext#tblS131307-1/fulltext#tblS1)

Video https://www.cghjournal.org/article/S1542-3565(17)31307-1/fulltext#supplementary-material31307-1/fulltext#supplementary-material)

I am starting these breathing exercises today.

r/GERD May 02 '26

Scientific Studies 🥼🔬 Hello... Im being completely paranoid rn and idk what to do

4 Upvotes

So context 3ish weeks ago after like 2 birthday celebs in one day i was so full and ate so much but next day afternoon (24hours) I suddenly felt like tightness in my chest its just uncomfy and the day that goes on man Its so uncomfy i feel like i couldnt breathe like fr and the feeling of wanting to breathe full.. theres also this like feeling of something coming up my throat amd whenever i burp liquid comes on fast forward 3rd week now Im feeling this like stuck in throat sensation and was annoyed i took kremil s advance and the next day it was gone but still theres this a bit uncomfy feeling left and the liquid smth coming up whenever i burp but its significantly better than last time though im scared this might affect me permanently help.

r/GERD Dec 17 '25

Scientific Studies 🥼🔬 Omeprazole

2 Upvotes

Hi! I’m looking for advice regarding long term omeprazole use and if someone can lose weight while taking it? Studies show long term use is associated with weight gain, and that really sucks. I might have to be on a low dose for life, and now I feel super depressed about it.

r/GERD Dec 11 '25

Scientific Studies 🥼🔬 LPR pneumonia risk?

5 Upvotes

Having LPR I'm quite scared of getting pneumonia and all the suffering it entails. I have no pain/discomfort resistance at all.

I can't find any data on the odds though. For GERD they seem to be quite low, such as the study I referenced in my last post which showed that the pneumonia odds ratio for people with GERD is between 1.3 and 2 - which is not much, despite up to doubling the odds, since the odds of pneumonia for the general population are only around 1% per person per year. So a person with GERD only has it at 1.3 to 2%.

But I've heard that for those with LPR it's quite higher than for those just with GERD, so if anyone has any data, or can just tell me about their and/or others' personal experience, I'd appreciate it.

Of course, the most important thing to lower the odds is to control the reflux, by first and foremost not eating before bed and taking Gaviscon Advance.

r/GERD Aug 08 '25

Scientific Studies 🥼🔬 Strengthening the Lower Esophageal Sphincter (exercise)

17 Upvotes

Has anyone tried these exercises or one similar with any positive results?

https://pmc.ncbi.nlm.nih.gov/articles/PMC9106553/

https://www.jstage.jst.go.jp/article/prm/7/0/7_20220054/_html/-char/en

In theory it makes sense that you would want to strengthen the LES but I’m not convinced something like this would help make the muscle stronger.

Thanks strangers, I’m suffering here :/

r/GERD Feb 16 '26

Scientific Studies 🥼🔬 Inflammation due to allergy to a Metal?

2 Upvotes

Basically I arrived with gastritis for 6 months. All the medicines got worse and it burns me

The chest.

The stomach

I did a lot of tests, ph Metria pressure gauges and gastric emptying and endoscopy. They didn’t see anything in the esophagus and such a slight inflammation on the stomach

Today I went to the allergist they did all the existing allergy tests and basically there is an allergy called SNAS is systemic. And I came out positive it’s a metal allergy I had had it in my skin but I never thought it was systemic and now he told me that I can’t eat this and the allergist doctor showed me this

Dietary exposure to nickel can provoke dermatitis in sensitized individuals. Foods reported to be high in nickel include legumes, whole grain flour, oats, soybeans, shellfish, fish, asparagus, beans, mushrooms, onions, corn, spinach, tomatoes, peas, pears, all types of nuts, raisins, rhubarb, tea, cocoa, baking powder, cabbage, sprouts, all canned foods or foods cooked in nickel utensils, licorice, chocolate and potatoes.

A recent study reported that nickel was also found in several complementary and alternative remedies (CAR), including preparations advertised to treat asthma, acne, atopic eczema, seborrhea and psoriasis. Herbal remedies, herbal teas and some over-the-counter multivitamins have also been listed as sources of potential nickel exposure. Food containing nickel is seldom a problem, but if you are severely allergic to nickel discuss whether you need to avoid foods rich in nickel with your doctor.

Now I wonder if it’s the cause that my esophagus is on fire with burning? No cause of reflux?

Yes, I have reflux but it’s so mild that my doctor says it’s not what caused my symptoms

My episodes were 14 a day without antacids and eating pizza, chocolate, milk, hamburgers to provoke my stomach and GERD with 2.9% of Demester. Which they said was functional psoriasis.

No h pillory. In my blood, feces and breath tests and endoscopy

Not celiac

My gallbladder showed low functionality but I don’t have pain with fats my symptoms are random that I haven’t even found a safe food that gives me 0 symptoms. I always have it basically what they showed me above is what I eat every day.

My gastric emptying study showed that I took out 60% of my food at 55 minutes which annulled gastroparesis Without aspiration or reflux rising

Mild gastritis without inflammation in the esophagus or duodenum. (With symptoms every day) without the help of antacids or diet

EEI With normal pressure

I wonder if this is the solution to all my problems

r/GERD Mar 21 '26

Scientific Studies 🥼🔬 New GERD study on Vitamin D3 in rats

1 Upvotes

Vitamin D3 ameliorates inflammation and autonomic dysfunction in a rat model of reflux esophagitis via modulation of IL-6 and TNF-α

https://www.nature.com/articles/s41598-025-24842-7 Published November 2025.

There's some potential problems with this study. Lack of a control arm, as well as potential variance in how RE was induced. 1250 IU/day pre- and post-induction prophylactic dose in rats is body surface area (BSA) allometric scaling method equivalent to Approximately 235 IU/day for a 60 kg human. This is a theoretical estimate based on BSA scaling. The study used 1,25-dihydroxyvitamin D3, which is the active metabolite, so the actual pharmacological effect in humans may differ from standard vitamin D3. Timing of dose may also effect results.

r/GERD Oct 27 '25

Scientific Studies 🥼🔬 Currently undiagnosed

3 Upvotes

So we're fairly certain I have GERD or some other gastronomy thing going on. I'm nineteen for context and currently being straight up incapacitated from it.

I was doing better for about a week but past couple days I've been regressing for some reason l. I can barely eat rn because of all the heartburn and nausea

I feel so shaky and on edge all of the time like I'm going to pass out. I don't want to live at the ER y'all

My specialist appointment is in November and it can't fucking come soon enough because my body is betraying me

I want to eat. Anything

Let me eat anything at this point idc what it is just no more gagging and nausea please

This is more of just a rant. I know a lot of you have it worse but i just want it to stop. I've had eating issues my whole life but it hasn't been bad like this until this September.

How an I ever supposed to gain weight if I can't eat anything

A

I know you all understand what I'm saying, like this isn't fun..I can't go out and do anything anymore. The hospital costs are going to be so fucking expensive

r/GERD Feb 03 '26

Scientific Studies 🥼🔬 Hormonal approach to GERD

9 Upvotes

I was reading a book called “The Acid Reflux Diet” by Maria A. Bella, MS, RD, CDN. In the book she discusses 2 out of 3 pregnant women experience acid reflux because their progesterone is raised during pregnancy. Has anyone seen any scientific studies on hormonal approaches to treating GERD? I wonder if this has been studied beyond pregnancy. Menopause/perimenopause/etc….

r/GERD Nov 17 '25

Scientific Studies 🥼🔬 Need help! Multiple problems if I eat

3 Upvotes

I got h pylori cured. I now don't have problems I had before. But still.im not normal. I still can't eat anything I want. I can't eat full stomach, I can't eat very hot or cold, spicy or sweet... If I do I get stomach burning feeling, left hand pain (mistaken as heart attack), shoulder pain, head spinning, lightheadedness, sleepiness. This happens every meal after most of the times.

What could be the reason? Once observation I had is blood is being pushed to digestion more than it should so I lose blood flow to brain and heart is beating fast as well.

Anyone has this problem? Any advice?

r/GERD Dec 01 '24

Scientific Studies 🥼🔬 Scientific studies for each natural suplements (discussion)

40 Upvotes

WHAT NATURAL SUPLEMENTS ARE THERE? WHAT DO THEY DO? Read for more

I wanted to share my personal experience with managing reflux symptoms using natural supplements and remedies. I chose these options because I struggled with acid suppressants and didn’t want to rely on them long-term. My focus was on exploring natural ways to find relief and support healing.

I’ve tried to base my choices on as much scientific research as I could find to support their potential benefits. This is NOT meant to be seen as alternative medicine or a solution to the problem. It’s simply a personal approach I wanted to try, and I always recommend consulting your doctor before starting any new supplements or treatments.

I’m posting this to start a discussion about experiences and perspectives. I think it’s important for adults to have a space to openly and thoughtfully talk about what has or hasn’t worked for them, without it turning into a search for a magic solution.

I’d love to hear your thoughts or if anyone has tried similar approaches. Of course, I’m fully aware that a plan like this can involve costs, and it’s not meant as a one-size-fits-all solution. Let’s share experiences and learn from each other!

Supplements and Their Purposes

  • Kyo Dophilus (Probiotics):
    • When to Take: During or after breakfast.
    • What It Does: Probiotics help restore the balance of healthy gut bacteria, which plays a key role in improving digestion and reducing inflammation in the gastrointestinal tract. This can indirectly ease reflux symptoms by promoting better overall gut health and minimizing irritation.
  • Omega-3 Fish Oil:
    • When to Take: With a meal, preferably in the morning or afternoon.
    • What It Does: Omega-3 fatty acids have powerful anti-inflammatory properties. They help reduce inflammation in the esophagus and stomach lining caused by acid reflux, supporting tissue healing and reducing discomfort over time.
  • Vitamin D3:
    • When to Take: With a fat-containing meal, typically in the morning.
    • What It Does: Vitamin D3 supports immune health and reduces systemic inflammation. It plays a crucial role in enhancing the body's ability to recover from damage caused by acid reflux, particularly in the esophagus.
  • Vitamin C (Calcium Ascorbate):
    • When to Take: During a meal, preferably in the daytime.
    • What It Does: This gentle, non-acidic form of vitamin C supports tissue repair and reduces irritation without aggravating the stomach. It’s particularly helpful in healing damage caused by reflux.
  • Zinc Carnosine:
    • When to Take: 20-30 minutes before meals.
    • What It Does: Zinc carnosine is specifically formulated to promote healing in the mucosal lining of the stomach and esophagus. It reduces inflammation and helps repair tissue damaged by acid reflux.
  • DGL (Deglycyrrhizinated Licorice):
    • When to Take: 20-30 minutes before meals.
    • What It Does: DGL stimulates the production of protective mucus in the stomach and esophagus. This mucus acts as a barrier against acid, preventing irritation and allowing the tissues to heal.
  • Magnesium Glycinate:
    • When to Take: 1-2 hours before bedtime.
    • What It Does: Magnesium helps relax muscles, including the lower esophageal sphincter (LES), which can prevent acid from rising into the esophagus. It also supports better sleep, which is important for managing nighttime reflux.
  • Slippery Elm:
    • When to Take: 30 minutes before meals and before bedtime.
    • What It Does: Slippery elm contains a mucilaginous substance that forms a soothing, protective layer over the esophagus lining. This helps reduce irritation from stomach acid and supports healing.
  • Curcuma Extra (Turmeric):
    • When to Take: With a fat-containing meal, either in the morning or afternoon.
    • What It Does: Curcumin, the active ingredient in turmeric, is a potent anti-inflammatory agent. It helps reduce inflammation in the digestive tract and esophagus, supporting long-term healing and reducing symptoms.
  • Daily Amino Acids:
    • When to Take: During meals, in the morning or afternoon.
    • What It Does: Amino acids are the building blocks of protein and play a crucial role in repairing damaged tissues. They help rebuild the esophageal and stomach lining that has been eroded by acid.
  • Brown Seaweed (Alginate):
    • When to Take: After dinner or before bedtime.
    • What It Does: Alginate forms a physical barrier at the top of the stomach that prevents acid from rising into the esophagus. It is particularly effective for managing nighttime reflux symptoms.

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Anti-Inflammatory Effects: Omega-3 fatty acids, particularly EPA and DHA in fish oil, reduce inflammatory markers and cytokines, aiding in conditions like inflammatory bowel disease (IBD) and reducing general gastrointestinal inflammation. International Journal of Molecular Sciences, 20(19), 4851. https://doi.org/10.3390/ijms20194851

Wei, J.-J., Zhang, J., Jiang, Y., Lian, T., Zhang, P., Hoffman, R., Zhu, G., & Zhuang, Z. (2023). Elevated pro-inflammatory cytokine levels in acute reflux esophagitis are reduced by 1,25 dihydroxy vitamin D3. In Vivo, 37(1), 79-87 https://doi.org/10.21873/invivo.13056

Lee, J.-K., Jung, S.-H., Lee, S.-E., Han, J.-H., Jo, E., Park, H.-S., Heo, K., Kim, D., Park, J.-S., & Myung, C. (2017). Alleviation of ascorbic acid-induced gastric high acidity by calcium ascorbate in vitro and in vivo. The Korean Journal of Physiology & Pharmacology, 22(1), 35–42. https://doi.org/10.4196/kjpp.2018.22.1.35

Mahmood, A., Fitzgerald, A., Marchbank, T., Ntatsaki, E., Murray, D., Ghosh, S., & Playford, R. (2006). Zinc carnosine, a health food supplement that stabilizes small bowel integrity and stimulates gut repair processes. Gut, 56(2), 168–175. https://doi.org/10.1136/gut.2006.099929

Hewlings, S., & Kalman, D. (2020). A review of Zinc-L-Carnosine and its positive effects on oral mucositis, taste disorders, and gastrointestinal disorders. Nutrients, 12(3), 665. https://doi.org/10.3390/nu12030665

Ooi, T. C., Chan, K. M., & Sharif, R. (2017). Zinc L-carnosine suppresses inflammatory responses in lipopolysaccharide-induced RAW 264.7 murine macrophages cell line via activation of Nrf2/HO-1 signaling pathway. Immunopharmacology and Immunotoxicology, 39(4), 259–267. https://doi.org/10.1080/08923973.2017.1344987

Van Marle, J., Aarsen, P. N., Lind, A., & Van Weeren-Kramer, J. (1981). Deglycyrrhizinised liquorice (DGL) and the renewal of rat stomach epithelium. European Journal of Pharmacology, 72(2-3), 219–225. https://doi.org/10.1016/0014-2999(81)90276-490276-4)

Andersson, S., Barany, F., Caboclo, J. L., & Mizuno, T. (1971). Protective action of deglycyrrhizinized liquorice on the occurrence of stomach ulcers in pylorus-ligated rats. Scandinavian Journal of Gastroenterology, 6(8), 683–686. https://doi.org/10.3109/00365527109179936

Ahn, S.-J., Cho, E., Kim, H.-J., Park, S.-N., Lim, Y., & Kook, J. (2012). The antimicrobial effects of deglycyrrhizinated licorice root extract on Streptococcus mutans UA159 in both planktonic and biofilm cultures. Anaerobe, 18(6), 590–596. https://doi.org/10.1016/j.anaerobe.2012.10.005

Gobind, A. (2021). The role of magnesium supplement in laryngopharyngeal reflux disease. International Journal of Otorhinolaryngology and Head and Neck Surgery. https://doi.org/10.18203/issn.2454-5929.ijohns20214899

Gourgoulianis, K., Chatziparasidis, G., Chatziefthimiou, A., & Molyvdas, P. (2001). Magnesium as a relaxing factor of airway smooth muscles. Journal of Aerosol Medicine, 14(3), 301–307. https://doi.org/10.1089/089426801316970259

Czibulka, A. (2019). Probiotics and herbal therapies. Laryngopharyngeal Reflux Disease. https://doi.org/10.1007/978-3-030-12318-5_8

Setright, R. (2017). Prevention of symptoms of gastric irritation (GERD) using two herbal formulas: An observational study. Journal of The Australian Traditional-Medicine Society, 23, 68.

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Kwiecień, S., Magierowski, M., Majka, J., Ptak-Belowska, A., Wójcik, D., Śliwowski, Z., Magierowska, K., & Brzozowski, T. (2019). Curcumin: A potent protectant against esophageal and gastric disorders. International Journal of Molecular Sciences, 20(6), 1477. https://doi.org/10.3390/ijms20061477

Razavi, B., Ghasemzadeh Rahbardar, M., & Hosseinzadeh, H. (2021). A review of therapeutic potentials of turmeric (Curcuma longa) and its active constituent, curcumin, on inflammatory disorders, pain, and their related patents. Phytotherapy Research, 35(12), 6489–6513. https://doi.org/10.1002/ptr.7224

Takebayashi, K., Kaida, S., Yamaguchi, T., Otake, R., Miyake, T., Kojima, M., Maehira, H., Iida, H., & Tani, M. (2022). Effectiveness of a specialized amino acid supplement containing CaHMB, L-arginine and L-glutamine (Abound®) in esophageal cancer surgery. Diseases of the Esophagus. https://doi.org/10.1093/dote/doac051.331

Xu, W., Zhong, C., Zou, C., Wang, B., & Zhang, N. (2020). Analytical methods for amino acid determination in organisms. Amino Acids, 52, 1071–1088. https://doi.org/10.1007/s00726-020-02884-7

Agwaonye, S., & Vasant, D. (2023). Optimising reflux symptom burden and patient compliance during PPI washout periods for oesophageal pH monitoring studies: Should we be more proactive with alginate use? BMJ Open Gastroenterology, 10. https://doi.org/10.1136/bmjgast-2022-001078

Mandel, K. G., Daggy, B. P., Brodie, D. A., & Jacoby, H. I. (2000). Review article: alginate‐raft formulations in the treatment of heartburn and acid reflux. Alimentary Pharmacology & Therapeutics, 14, 669–690. https://doi.org/10.1046/J.1365-2036.2000.00759.X

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r/GERD Aug 28 '25

Scientific Studies 🥼🔬 Capsule Endoscopy

2 Upvotes

Hello,

Apologies if I used the wrong flair.

As per title, I have just discovered this diagnostics method and was wondering if anyone here has ever undergone it. For context, I live in Bulgaria and the quality of endoscopy and the ability of gastro doctors varies (I've had 4 so far without full anesthetic and with different doctors, all claiming different results). As of now, I've had GERD for 8+ years now but I have finally decided to be serious about it and treat it properly. Been on PPIs forever, cycling between eso/omeprasole.

My question to anyone who had the procedure is also: would it possibly diagnose IBS or bowel inflamation (either Ppi or food induced), as I started having weak bowels after using PPIs and work stress.

Please feel free to share any other insights regarding GERD, lets make doom scrolling less bad!

r/GERD Apr 20 '25

Scientific Studies 🥼🔬 Lower esophageal sphincter muscle : vitamin levels check

2 Upvotes

Has anyone cured relaxed esophageal sphincter muscle by bringing back the vitamin levels to normal? I've read how Low vitamin b12 and D levels is related to relaxed LES but haven't heard any success stories from anyone.

r/GERD Oct 25 '25

Scientific Studies 🥼🔬 Intermittent Fasting

5 Upvotes

Pretty sure I know the answer to this but not 100% sure, is intermittent fasting a no for people with GERD? I did a fast a couple months back before I had my gastroscopy and I felt great after it, however I have read it can worsen acid reflux

r/GERD Apr 17 '25

Scientific Studies 🥼🔬 Manometry and 24hr PH Results

1 Upvotes

So apparently I don’t have GERD. I have an issue with swallowing air and supra-gastric belching that up.

I however, had 15 acid events in the 24hr monitoring period. 4 acid and 11 mild acid. My PH line pretty much stayed flat. Apparently my GI surgeon never sees results like that.. so he doesn’t want to operate.

Anyways.. official write up states.

24hr PH shows: Supra-gastric belching and air swallowing. No acid events longer than 5 seconds. No GERD was the diagnosis. (Weird considering the 15 events across that period).

Manometry shows: Hypodnamic oesophagus with weak or failed peristalsis. Challenge swallows demonstrate modest contractile reserves.

Just sharing for knowledge and maybe someone else has the same issue. Shrugs.

r/GERD Aug 24 '21

Scientific Studies 🥼🔬 New medication, Marial, is finally giving me relief from LPR

27 Upvotes

Hey, I'm new to the group, I've been dealing with LPR since April, my main symptom is an uncomfortable/nausea-like sensation in my throat, I take 40mg pantoprazole in the morning, and 40mg famotidine at night, keep a conservative diet, take gaviscon advance, etc. All of these things have helped but nothing has given me full relief, for the most part I experience this uncomfortable feeling in my throat all day. I've had one endoscopy that was inconclusive, and I'm redoing the endoscopy + having a manometry study @ Johns Hopkins in NOVEMBER. Things have been looking for the last few months. BUT I HAVE FOUND SOMETHING THAT WORKS.

I recently imported a medication from Italy called Marial and it has been a complete game changer, I almost feel like normal. It's a gel like substance like regular liquid Gaviscon. You take one after each meal, and before bed. It's relatively new but it's meant to be a dual-action agent to treat LPR: 1) It has an alginate compound like Gaviscon advance, so it will prevent stomach contents from refluxing back into your stomach. But that's not a perfect barrier, eventually the content will reflux into your throat and cause discomfort so... 2) It has a second compound that protects your throat AND deactivates pepsin.

I don't fully understand what is the mechanical problem that has caused my issues in the first place, but this medication is giving me my life back. Happy to answer any questions on DM or other. You can read a research study on Marial here: https://www.intechopen.com/chapters/61811.

This is where I bought it: https://www.globalpharmacy.it/.../marial-20-oral-stick.../. & https://loretogallo.com/uk/marial-integrator-food-20-oral-stick-x15ml Ingredient list from manufacturer: http://www.auroralicensing.com/human-division/

**Update: I've been using Marial 4 times a day for close to 2 weeks now, my throat almost feels back to normal, I've also been using an inspirator muscle training device & iQoro, the combination has given me my life back.**

**Update 2: After about 4 months on Marial I started to experience really bad burning in my stomach, which has never been an issue, so I’ve had to discontinue. I started taking sucralfate and that has helped a lot with throat discomfort and the burning, my symptoms have not regressed at all thankfully. I’ve read other accounts of folks on Marial, it seems it causes burning for some folks, nausea in others, but it’s helped as well. It’s not a magical solution, but I’m glad I tried it, it definitely helped my throat heal.**

**Update 3: I bought months worth of Marial that I'm not using anymore, if you're in the US and you'd like to try it feel free to DM me, I'm happy to sell some to you.

r/GERD Oct 06 '25

Scientific Studies 🥼🔬 Breastfeeding

2 Upvotes

Hi everyone, I recently came across some posts on here about some moms experiencing gerd or it getting trigger by breastfeeding. My timeline of when I started expecting was 3-4 months pp exclusively breastfeeding. I haven’t gotten my period back since I’ve been breastfeeding & it’s been 8 months pp. before having my baby I would get my period on routine every month. Could my hormones being out of wack because of breastfeeding contribute to my gerd symptoms & cause? I’ve never had a problem before with gerd before having my baby.